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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
48.79
Human Site:
S406
Identified Species:
76.67
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
S406
G
T
H
T
A
M
K
S
G
I
L
A
A
E
S
Chimpanzee
Pan troglodytes
XP_517508
617
68419
S406
G
T
H
T
A
M
K
S
G
I
L
A
A
E
S
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
S406
G
T
H
T
A
M
K
S
G
I
L
A
A
E
S
Dog
Lupus familis
XP_853781
600
66768
S389
G
T
H
T
A
M
K
S
G
I
L
A
A
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
S405
G
T
H
T
A
M
K
S
G
S
L
A
A
E
S
Rat
Rattus norvegicus
Q6UPE1
616
68180
S405
G
T
H
T
A
M
K
S
G
S
L
A
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
S458
G
T
H
T
A
M
K
S
G
I
L
A
A
D
A
Chicken
Gallus gallus
NP_001026705
477
53116
K278
Q
S
Y
G
I
G
L
K
E
L
W
T
I
D
E
Frog
Xenopus laevis
NP_001087869
616
68418
S405
G
T
H
T
A
M
K
S
G
M
L
A
A
E
T
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
S406
G
T
H
T
A
M
K
S
G
M
L
A
A
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
A393
R
I
K
G
S
H
Y
A
M
K
S
G
M
L
A
Honey Bee
Apis mellifera
XP_624722
606
67014
S395
G
T
H
N
A
M
K
S
G
M
L
A
A
E
S
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
M385
L
K
G
T
H
N
A
M
K
S
G
M
V
A
A
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
S402
G
T
H
N
A
M
K
S
G
I
I
A
A
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
S403
G
T
H
T
A
M
K
S
G
L
L
A
A
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
0
86.6
86.6
N.A.
0
86.6
6.6
80
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
26.6
100
100
N.A.
20
93.3
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
80
0
7
7
0
0
0
80
80
7
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
0
0
74
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
0
7
14
0
7
0
0
80
0
7
7
0
0
0
% G
% His:
0
0
80
0
7
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
0
0
40
7
0
7
0
0
% I
% Lys:
0
7
7
0
0
0
80
7
7
7
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
7
0
0
14
74
0
0
7
0
% L
% Met:
0
0
0
0
0
80
0
7
7
20
0
7
7
0
0
% M
% Asn:
0
0
0
14
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
7
0
0
80
0
20
7
0
0
0
47
% S
% Thr:
0
80
0
74
0
0
0
0
0
0
0
7
0
0
14
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _